Headline, June 22 2021/ ''' '' STUDENTS FITNESS STUNNERS '' '''

''' '' STUDENTS FITNESS

 STUNNERS '' '''

FOR ALL : THE BEST TYPE OF EXERCISE? Blood tests may just hold all clues. Many enigmas intrigued researchers from Harvard University, the Beth Israel Deaconess Medical Center in Boston, and other institutions.

The scientists had long been interested in how exercise alters the molecular environment inside the body, as well as how those changes influence health, and how diverse the alterations can be.

For the new study, which was published in May, in Nature Metabolism, they decided to see if certain molecules in people's blood might be related to how their physiologies react to workouts. To find out, they turned first to a valuable trove of data produced during the large-scale Heritage study.

IF WE ALL BEGIN THE SAME exercise routine tomorrow, some of us will become much fitter, others will get a little more in shape, and a few of us may actually lose fitness.

Individual responses to exercise can vary wildly, and, until now, unpredictably. But a fascinating new study of more than 650 men and women suggests that the levels of certain proteins in our bloodstreams might foretell whether and how we will respond to various exercise regimens.

The study needs replication and expansion, but represents a meaningful start toward a blood test to indicate the best types of exercise for each of us, and if we can expect to gain more or less benefits from the same workout as our spouse, offspring or other training partners or rivals. 

Exercise response is a topic that probably should be discussed more often and openly than it is. We know exercise is wonderful for our health. Countless studies show that people who exercise tend to live longer, more happily and with less risk of many diseases than sedentary people.

But those findings refer to broad averages. Parse the study data and you can find a dizzying gamut of reactions, from outsized health and fitness gains in some people to none in others.

Dissemblingly, little about our bodies and lives currently predict how we will respond to exercise, including our genetics.

Identical twins, with identical DNA, can react quite differently to workouts, studies show, As can people who are equally lean, obese or aerobically fit at the start of new exercise program. Some more mysterious reasons wind up fitter and healthier afterward than others.

Using state-of-the-art molecular tools, the scientists began enumerating the numbers and types of thousands of proteins in each of the 654 people's bloodstreams. Then they tabulated those figures with data about everyone's aerobic fitness before and after their five months of exercises.

And clear patterns emerged. The levels of 147 proteins were strongly associated with people's baseline fitness, the researchers found. If some of those protein numbers were high and others low, the resulting molecular profiles indicated how fit someone was.

More intriguingly, a separate set of 102 proteins tended to predict people's responses to exercise, Higher and lower levels of these molecules - few of which overlapped with the protein related to people's baseline fitness - prophesied the extent of someone's aerobic capacity would increase, if at all, with exercise.

Finally, because aerobic fitness is so strongly linked to longevity, the scientists crosschecked levels of the fitness related proteins in the blood of people enrolled in separate health study that included mortality records, and found that protein signatures implying lower or greater fitness response likewise signified shorter or longer lives.

Taken as a whole, the new study's results suggest that ''molecular profiling tools might help to tailor'' exercise plans, said Dr. Robert Gerszten, a professor of medicine at Harvard Medical School and chief of cardiovascular medicine at Beth Israel Deaconess Medical Center, who conducted the new study with its lead author, Dr. Jeremy Robbinsand others.

Someone whose bloodstream protein signature suggests how he or she might gain little fitness from a standard, moderate walking, cycling or swimming routine, for instance, might be nudged toward higher-intensity workouts or resistance training Dr. Gerszten said.

This area of research is still in its infancy, he and Dr. Robbins said. Scientists will need to to study far more people, with far broader disparities in their health, fitness, age and Lifestyles, to zero in on which proteins matter most.

The researchers hope, too, to backtrack and find where those molecules originated, to better understand how exercise remakes our bodies and molds our health.

The Honor and Serving of the Latest Global Operational Research on Students, Fitness and ongoing Research, continues. The World Students Society thanks author Gretechen Reynolds.

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