4/22/2019

Headline April 23, 2018/ '' ' GENETIC OBESITY GERMAIN ' ''


'' ' GENETIC OBESITY GERMAIN ' ''




HEROES OF THE WORLD STUDENT SOCIETY : Beautiful as they are, and always will  be..............

Merium, Rabo, Aqsa have to stay alert for any propensity to gain weight.  Dee, has to keep her guards very up for other signs.

Haleema and Saima and Sarah and Zilli, must stay very concerned for other genetic messages and catch the early signs.

Hussain - got to the wisdom earlier, and just about every day, he continues his serious grappling with  genetic issues by running over 6 kilometers. Come Hell or Fire.

Students Dantini [Malyasia], and Faraz best wake up, before they run into some very serious, serious problems.

CAN A GENETIC TEST identify newborns at risk of becoming severely obese by middle age?

Researchers say they have come up with one, and that  it might allow interventions in childhood to avoid that fate.

The test examines more than 2 million spots in a person's genetic code, seeking variants that individually nudge a person's obesity risk up by a tiny amount.

The researchers drew on previously published data about those variants to create a risk score.

A high score didn't guarantee obesity, nor a low score rule it out.

But middle-aged people with scores in the top 10 percent were 25 times as likely to be severely obese as those in the bottom 10 percent, scientists reported in a paper released Thursday by the journal Cell.

Those two groups were separated by an average weight difference of about 29 pounds [13 kilograms]  researchers said.

Analysis showed the genetic propensity to obesity began having effect on weight around age 3. Up to about age 8, ''you might be able to make a difference in the kids who are born susceptible to obesity,'' said one author of the study, Dr. Sekar Kathiresan of Massachusetts general Hospital in Boston and the Broad Institute of MIT and Harvard.

But it will take further research to see whether intervening would work, Dr. Sekar Kathiresan said.

The results for middle-age came from a study 288,000 people.

Overall, the risk -score research included data from more than 300,000 people at various ages. Severe obesity was defined as a body mass index of 40 or more.

Results show genetic inheritance ''plays a large role in how heavy one gets,'' Katheresan said.

The risk score probably takes about half of a person's genetic propensity into account, he said, and it shows similar accuracy in predicting ordinary ordinary obesity, defined as a BMI of 30 or more.

Even if one inherits a propensity for obesity, he said:

''You still have control over your fate. You are not fated to be obese, but it's very clear those individuals who've inherited susceptibility have to work that much harder to keep the weight off.''

Among study participants - with the highest scores, he noted, 17 percent were of normal weight.

Other analyses show that people who remain lean despite an inherited propensity for obesity tend to eat better and have more physical activity than others with with a high score who got fat.

''So you can do something about it,'' he said.

Ruth Loos, a  professor of environmental medicine and public health who did not participate in the study, said, the risk score explains more of people's genetic tendency than previous studies did. But she doubted it would be useful in doctor's office.

It is ''never going to be a good predictor,'' said Loos, of the Icahu Scool of Medicine at Mt. Sinai in New York.

She noted that on one test of the score's predictive power, only 58 of the 371 subjects scoring in the top 10 percent ended up severely obese.

And many other severely obese people didn't score in the top 10 percent, she said.

The Honor and Serving of the latest Operational Research on 'Obesity and Genetics', continues. The World Students Society thanks the Agencies.

With respectful dedication to the  Students, Professors and Teachers of the world. See Ya all prepare for 'Great Global Elections' and ''register'' on : wssciw.blogspot.com  and Twitter -!E-WOW! - the Ecosystem 2011:

''' Love & Life '''

Good Night and God Bless

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