4/19/2019

HEART : ''*FIRST 3D* PRINT''


TEL AVIV : Scientists hope 'major breakthrough'' will advance possibilities for transplants.

Scientists in Israel unveiled a 3D print of a heart with human tissue and vessels on Monday, calling it a first and a ''major medical breakthrough'' that advances possibilities for transplants.

While it remains a far off, scientists hope one day to be able to produce hearts suitable for transplant into humans as well as patches to regenerate defective hearts.

The heart produced by researchers at Tel Aviv University is about the size of rabbit's.

It marked ''the first time anyone anywhere has successfully engineered and printed an entire heart replete cells, blood cells, ventricles and chambers,'' said Tal Dvir, who led the project.

''People have managed to 3D-print  the structure of heart in the past, but not with the cells with blood vessels,'' he said.

But the scientists said that many challenges remain before fully working 3D printed hearts will be available for transplants into patients.

Journalists were shown a 3D print of a heart about the size of a cherry at Tel Aviv University on Monday as the researchers announced their findings, published in the peer-reviewed journal Advanced Science.

Researchers must now teach the printed hearts ''to behave'' like the real ones.

The cells are currently able to contract, but do not yet have the ability to pump.

Then they plan to transplant them into animal models, hopefully in about a year, said Dvir.

''Maybe, in 10 years, there will be organ printers in the finest hospitals around the world, and these procedures will be conducted routinely,'' he said.

But he said hospitals would likely to start with simpler organs than hearts.

Producing 'ink'
In its statement anoouncing the research, Tel Aviv University called it a ''major medical breakthrough.'' A biopsy of fatty tissue was taken from patients that was used in the development of the ''ink'' for the 3D print.

First, patient specific cardiac patches were created followed by the entire heart, the statement said. Using the patient's own tissue is important to eliminate the risk of an important provoking an immune response and being rejected, Dvir said.

Challenges that remain include how to expand the cells to have enough tissue to recreate a human-sized heart, he said.

Current  3D printers are also limited by the size of their resolution and another challenge will be figuring out how to print all small  blood vessels.

3D printing has opened up possibilities in numerous fields, provoking both promise and controversy.

The technology has developed to include 3D prints of everything from homes to guns. [AFP]

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