Headline Oct 15,2012/


And that's truly, masterly complex work by nature: growing an entire human being in nine months. This is the miracle of life! And then are people like Lee Spievack' who severely damage or lose a limb, a finger or a body part. The answer for them is either a prosthesis or a nub. That's because the adult human body is evolved to scar, avoiding infection and moving on with life. But that life would be a lot better for a lot of people if their bodies could be manipulated into fixing and replacing lost or damaged body parts -similar to what happens to fetuses the first few months in the womb.

If a fetus looses an arm or a leg it grows right back. So if you think about it that way, you can say we just want an arm, you know, or we want a leg. And the Scientists at the Regenerative research think: So just give us enough information and we can do that.

A week later the Professor called Allan in again and said he had project for him. He took him down to the nearby Kokosing river, got him into the water, and taught him how to catch what appeared to be tiny black insects, where were salamander larvae. Spievack's assignment: raise them, then snip of their arms,legs, and tails, taking notes for how long it takes for them to grow back.Salamander's can regenerate almost any part of their bodies. Cut their legs and they grow back. Gouge an eye and a new one regenerates. Amazing miracle!

Alan Spievack took his Professor's career advise on regeneration, won a Fulbright scholarship, and went to Harvard Medical School for a distinguished career in surgery. Then fate intervened and he attended a lecture given by Professor Stephen Badylak, who by then had become an expert on the biological components of the intestine -like the fact that the inner lining of the intestine regenerates itself every six days.

Badylak honed in on the layer of the intestine that supported the tissue replacement, called the submucosa. He put the submucosa in other wounded organs in dogs, and the same thing happened. Achilles tendons grew back. Urinary bladders grew back. The implications of the discovery were profound: The submucosa stopped the scarring process and promoted regrowth. Badylak determined that the intestinal material was an extracellular matrix -the part of tissue in the body that connects cells to one another, like a scaffold. Only this extracellular matrix from the small intestine -he would later use a similar lining from the bladder -tricks the body's cells into rebuilding instead of scarring. It is like the cells are in the womb again, and the extracellular matrix alerts them that the Achilles tendons are not yet done.

The cells kick into gear and get to work. And they are then joined by stem cells, -those all powerful building blocks of life capable of growing into any tissue in the body! Miracle good and pure!

And before I round off the post, it maybe appropriate to inform you all, that I got to the bedside honour of Malala Yusafzai at the Hospital. Like the whole Planet I prayed!

I then walked over the Nursing Station and left a beautiful bouquet of flowers from the ''Students of the Entire Loving World!''

Good night & God bless!

SAM Daily Times - the Voice of the Voiceless


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