Spider-Man's web-shooters can create yards and yards of
spider silk, but in real life, making such a strong, stretchy rope
hasn't been easy.
Now, science has come one step closer to fiction with silkworms that spin spider silk.
New
genetically modified silkworms produce cocoons incorporating the
stretchier, stronger fibers spiders use to spin their webs, according to
a new study.
"Our hope was that by embedding spider-silk protein [gene] sequences
within silkworm silk [gene] sequences, we could get those proteins to
co-assemble ... into composite fibers, and that is what happened," said
study co-author Don Jarvis, a molecular biologist at the University of Wyoming in Laramie.
Spiders create the best silk in terms of strength and elasticity. But
many species are territorial or cannibalistic, making them difficult to
farm.
That's why researchers have tried to insert spider-silk
protein gene sequences into other products, such as goats' milk and
hamster cells.
To make sure the genetic transformation was a success, the scientists
also added green fluorescent protein to the eggs, so that successfully
engineered silkworms would glow under blue light.
Surprisingly,
the worms' silk glands glowed even under normal light—which is "totally
amazing," said Jarvis, whose study appeared this week in the journal Proceedings of the National Academy of Sciences.
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